Short answer: No, not natively. The built-in Hyper-V Replica settings are hard-coded to intervals of 30 seconds, 5 minutes, or 15 minutes.
However, you can "hack" this behavior using PowerShell and Task Scheduler to force replication to occur only during specific windows.
The Workaround: Pause & Resume Scripts
You can effectively create a "low usage only" schedule by telling Hyper-V to pause replication during the day and resume it at night.
How to do it:
Create a "Stop" Script: Create a PowerShell script that runs in the morning (e.g., 8:00 AM) to pause replication.
Suspend-VMReplication -VMName "YourVMName"
Create a "Start" Script: Create a second script that runs at night (e.g., 2:00 AM) to resume replication.
Resume-VMReplication -VMName "YourVMName" -Resynchronize
Schedule Them: Use Windows Task Scheduler on the primary Hyper-V host to trigger these scripts at your desired times.
Critical Warnings
If you choose this method, you must be aware of significant risks that standard 15-minute replication avoids:
Massive Log Files (HRL): During the day, Hyper-V tracks every single change in a .HRL log file. If your server is busy, this file can grow to be hundreds of gigabytes by the time night comes. If you run out of disk space, your VM will pause or crash.
Long Sync Times: When replication resumes at 2 AM, it has to push an entire day's worth of data at once. If the "low usage" window isn't long enough to transfer that data, replication will fail or bleed into the next day.
Data Loss Risk (RPO): If your primary server crashes at 5:00 PM, you will lose all data changed since the previous night's replication. You lose the primary benefit of replication (near real-time recovery).
Better Alternatives
If you only want to move data once a day, you are likely looking for Backup rather than Replication.
Standard Backups: Use Veeam, Altaro, or Windows Server Backup to take a nightly incremental backup. This is designed for daily intervals and handles the "snapshot" cleanup much better than a paused replica.
Third-Party Replication: Tools like Veeam Backup & Replication allow you to schedule replication jobs explicitly (e.g., "Run daily at 3 AM") without the risks of manual pausing.
This video is relevant because it visually demonstrates the "Pause" and "Resume" replication functions in the Hyper-V manager, which are the exact controls you would need to automate for a custom schedule.